CGR Event - 6217 - Feldman - VKORC Gene Test for Coumadin Dosage

Continuing Medical Education

To participate in this event:
1. Read CME information.
2. View course materials.
3. Complete assessment.
4. Obtain CME credit.

VKORC Gene Test for Coumadin Dosage

Date of Online Release: August 26, 2008
Date of Original Grand Rounds: August 8, 2008
Credits: .75 AMA PRA Category 1 Credit™
See link to Course Materials below.

CME Information - Overview

Testing for polymorphisms in the VKORC gene and the CYP2C9 gene has recently been endorsed by the FDA as an appropriate medical practice to optimize the dose of Coumadin. The physiologic bases for this test are reviewed, as well as the proper interpretation of the genetic data in the clinical setting.

Educational Objectives
The intended result of this activity is increased knowledge. At the conclusion of this program, participants should be able to-

Cite why genotyping for VKORC and CYP2C9 may be useful for patients who are being started on Coumadin therapy.
Describe the physiological mechanism underlying the genetic associations.
List the strengths and limitations of the VKORC/CYP2C9 genotyping assay.
Review the results of the VKORC test reports and be able to utilize the test in clinical practice.

Target Audience
The intended audience for this continuing medical education activity includes cardiologists, internists, and others involved with patients who need Coumadin for anticoagulation.

Method of Instruction / Participation
This online enduring material comprises slide sets with text and audio derived from a live cardiology grand rounds presentation with post activity assessment and evaluation.

Evaluation / Feedback
We value your comments; please send your suggestions and comments to the office of continuing medical education at Texas Heart Institute.

Speaker

Dr. David Feldman

David Feldman, MD
Staff Physican, Department of Pathology
St. Luke's Episcopal Hospital
Houston, Texas

Accreditation / Credit Designation

Texas Heart Institute is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The Texas Heart Institute designates this educational activity for a maximum of .75 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Estimated Study Time
The estimated time to complete this activity, including review of the materials and completion of the course assessment is 45 minutes.

Repurposing Statement
If you previously completed and received credit for the live CME-sponsored grand rounds entitled, The VKORC Gene Test for Coumadin Dosage, on August 8, 2008, please note that you will not receive credit for completing this activity. Participants who take part in an identical activity, even in order to validate learning or to clarify specific topics, cannot claim, nor will the Texas Heart Institute award, duplicate credit for the activity.

Term of Approval
August 26, 2008 through August 26, 2011. Continuation of CME credit from August 26, 2011 depends on a thorough review of the content for currency and accuracy.

Peer Review
In August 2008, this continuing medical education activity was reviewed for currency and accuracy of content by Patrick J. Hogan, MD, FACC, Director, Learning Resource Center and Co-Chairman, Medical Education Committee—Texas Heart Institute, Houston, Texas.

Disclosure of Relationships
It is the intent of the Texas Heart Institute to ensure that its educational mission and its continuing medical activities in particular, should not be influenced by the special interests of individuals associated with its program.

Faculty Disclosure
In accordance with the guidelines of the Accreditation Council for Continuing Medical Education, faculty members have disclosed their relationships, either with one or more of the manufacturers of commercial products discussed, or with one or more of the corporate organizations offering educational grants for the live continuing medical education activity.

Dr. Feldman discloses the following, relevant to this program: Employee/Salary—Gulf Coast Pathology Associates.

Course Materials and CME Credit

This online enduring material comprises one presentation. By clicking on the Course Materials link below, you acknowledge that you have reviewed the CME information provided above. After viewing the presentation, you must complete an assessment and evaluation to obtain CME credit for this activity.

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